Sulbutiamine was developed in Japan as a more efficient version of vitamin B1. vitamin B1 (thiamine) is an essential nootropic vitamin and sulbutiamine mimics the effects of Thiamine at a more drastic level. Sulbutiamine is more efficient than thiamine at crossing the blood brain barrier and therefore much stronger in terms of effects. Sulbutiamine brings its own set of unique properties and can be used alone or stacked with other nootropics.
Sulbutiamine has long been used as an over-the-counter nootropic. Certain studies have pointed it to improving memory function. This is likely due to its influence on acetylcholine and glutamate activity. Influence of D1 dopamine receptor function may also aid in added cognitive benefits.
Sulbutiamine seems to have a mild stimulant effects in some. Many athletes were using it as a legal performance enhancer in sports and it is quite popular in these communities. Sulbutimaine does not seem to affect the other catecholamines other than dopamine so it does not have a tendency to trigger your typical amphetamine-stimulant side effects.
Sulbutiamine seems to have some powerful anti-depressant effects. This may be due to the effects subutiamine has on Dopamine and the D1 receptors. Reports of sulbutiamine and its effects on mood are incredibly common. It can act as a very powerful anti -depressant for short periods of time. These effects commonly recede after recurrent use so sulbutiamine shouldn’t be used primarily as an anti-depressant.